抖M女仆 Enrolling for Alzheimer鈥檚 Prevention Research Program
(Photo by Alex Dolce)
抖M女仆 in Boca Raton, Florida is now enrolling volunteer participants in a pioneering international Alzheimer鈥檚 disease prevention research program. The Alzheimer鈥檚 Prevention Initiative (API) Generation Program is made up of two clinical trials鈥擥eneration Study 1 and Generation Study 2鈥攁nd will test investigational study medications which aim to prevent the onset of Alzheimer鈥檚 disease in cognitively healthy people whose genetic makeup puts them at particularly high risk for developing the disease at older ages.
The number of people in Florida who are age 65 and older with Alzheimer鈥檚 disease is expected to increase 41.2 percent by 2025 to a projected 720,000, highlighting the urgency of finding a medical breakthrough. Alzheimer鈥檚 disease affects 11.5 percent of Medicare beneficiaries in Palm Beach County and 12.7 percent of Medicare beneficiaries in Broward County (a nearly 18 percent increase over national average). According to the Alzheimer鈥檚 Association, Florida is number one in per capita cases of Alzheimer鈥檚 disease in the United States. 抖M女仆 is one of approximately 190 sites globally participating in the API Generation Program.
鈥淲e are very excited to be a part of research that could significantly increase our understanding of Alzheimer鈥檚 and potentially benefit millions of people around the nation and the world who might be at risk of developing Alzheimer鈥檚 disease,鈥 said James E. Galvin, M.D., M.P.H., principal investigator of the Generation Program at 抖M女仆鈥檚 Comprehensive Center for Brain Health. 鈥淧articipating in research like the Generation Program is a great way to join the fight against this horrible disease.鈥
The API Generation Program is the first to incorporate both genetic testing and counseling. Prospective participants referred to the trial will be required to learn if they carry a specific gene that puts them at increased risk to developing Alzheimer鈥檚. Genetic counseling will be provided in person or by phone.
Participants will be recruited via multiple venues, including the Alzheimer鈥檚 Prevention Registry鈥檚 GeneMatch program (www.endALZnow.org/GeneMatch), a first-of-its kind program designed to identify a large group of people interested in volunteering for Alzheimer鈥檚 research studies, based in part on their genetic information.
To learn more about volunteering for the Generation Program at 抖M女仆鈥檚 Comprehensive Center for Brain Health, visit , call 561-297-0164, or go to www.GenerationProgram.com.
The Generation Program is sponsored by Novartis, a Swiss pharmaceutical company, and Amgen, a biotechnology company based in Thousand Oaks, CA, in collaboration with Banner Alzheimer鈥檚 Institute in Phoenix, AZ.
Alzheimer鈥檚 is a debilitating and incurable disease that is estimated to affect more than 46 million people worldwide according to Alzheimer鈥檚 Disease International.
About Study Site
The Comprehensive Center for Brain Health at 抖M女仆 provides personalized care for the prevention and treatment of a variety of brain disorders. The Center has a dual focus on diagnosis and prevention of neurodegenerative diseases such as Alzheimer鈥檚 disease, Parkinson鈥檚 disease, Lewy body dementia, frontotemporal degeneration, vascular cognitive impairment, and Chronic Traumatic Encephalopathy (CTE) and other related disorders and meeting the needs of family caregivers. The Center specializes in providing customized prevention plans for individuals who are concerned with their cognitive health and neurodegenerative disease risk. In addition, intensive medical management for those who are actively struggling with neurodegenerative disorders is offered. Evaluation, diagnosis, and treatment is provided by a transdisciplinary team led by world-renowned neurologist and researcher James Galvin, M.D., M.P.H.
About the Alzheimer鈥檚 Prevention Initiative
The Alzheimer鈥檚 Prevention Initiative (API) is an international collaborative formed to launch a new era of Alzheimer鈥檚 prevention research. Led by the Banner Alzheimer鈥檚 Institute, the API will conduct prevention trials in cognitively healthy people at increased genetic risk for Alzheimer鈥檚 disease. It will continue to establish the brain imaging and biological and cognitive measurements needed to rapidly test promising prevention therapies, and to provide registries to support enrollment in future prevention trials. API is intended to provide the scientific means, accelerated approval pathway, and enrollment resources needed to evaluate the range of promising Alzheimer鈥檚 prevention therapies and find ones that work without losing another generation. For more information, go to www.banneralz.org.
About GeneMatch
GeneMatch is a research program of the Alzheimer鈥檚 Prevention Registry to help identify individuals who are willing to participate in research studies based in part on their APOE genetic information, the major genetic risk factor for late-onset Alzheimer鈥檚 disease. The program is optional for people who are enrolled in the Alzheimer鈥檚 Prevention Registry. It will enroll people who are between 55 and 75 years of age, reside in the U.S., and do not have a diagnosis of dementia or other cognitive impairment syndrome. For more information, go to https://www.endalznow.org/genematch.
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